Table of Contents
1.
Are Statins A Panacea for Boned Arteries and Brittle Bones?
2.
Background
3.
Inhibition of the Mevalonate Pathway by Statins and Bisphosphonates
4.
Questions
5.
Statin Reduces Bone Resorption
6.
Statins and Bone Resorption
7.
Statin Induces Osteoclast Apoptosis
8.
Statins and Bone Formation
9.
Osteoblasts and Bone Morphogenetic Proteins
10.
Statins stimulate bone formation
11.
Simvastatin - Bone Morphogenetic Proteins and Osteoblast Differentiation
12.
Prospective Controlled Studies on Statins and Bone Markers
13.
Statins and BMD in Observational Studies
14.
Statins and BMD in Prospective Studies
15.
Statins and Fracture Risk
16.
Potential Explanations for Literature Conflicting Results
17.
Summary